Gene-Specific Effect of Beta-Adrenergic Blockade on Corrected QT Interval in the Long QT Syndrome
نویسندگان
چکیده
منابع مشابه
[The long QT interval syndrome].
The syndrome of long QT interval frequently follows to syncope or a sudden cardiac death on the basis of originated polymorphic ventricular tachycardia of the "torsade de pointes" type. The prolongation of the QT interval in the hereditary form is based on mutation of the genes responsible for the formation of sodium and potassium channels. The authors analyze the occurrence, clinical findings,...
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AIMS Beta-blockers are the standard of care for the treatment of long QT syndrome (LQTS), and have been shown to reduce recurrent syncope and mortality in patients with type 1 LQTS (LQT1). Although beta-blockers have minimal effect on the resting corrected QT interval, their effect on the dynamics of the non-corrected QT interval is unknown, and may provide insight into their protective effects...
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ژورنال
عنوان ژورنال: Annals of Noninvasive Electrocardiology
سال: 2013
ISSN: 1082-720X
DOI: 10.1111/anec.12048